Data Sources

Galen integrates 10+ biomedical databases into a unified knowledge graph. Each database contributes specific types of evidence — from drug bioactivity to clinical genomics to protein interactions.

ChEMBL

Drug activity

Bioactivity measurements for 2.4M+ compounds

cBioPortal

Clinical genomics

Somatic mutations across 498 cancer studies

STRING

Protein interactions

Protein-protein interaction networks (11M+ interactions)

UniProt

Protein function

Universal protein function annotations

Reactome

Biological pathways

Curated biological pathway database (2,600+ pathways)

ClinVar

Genomic variants

Clinical significance of genetic variants

IntOGen

Cancer driver genes

Cancer driver gene predictions across 28 tumor types

BioGRID

Genetic interactions

Genetic and physical interactions including synthetic lethality

GO

Molecular function

Gene Ontology functional annotations

TCGA

Cancer genomics

The Cancer Genome Atlas multi-omic data

PubMed

Biomedical literature

Biomedical literature mining (34.7M+ abstracts)

GTEx

Gene expression

Normal tissue gene expression across 54 tissues

ClinicalTrials.gov

Clinical trials

Active interventional trials matched by mutation, cancer type, and eligibility criteria.

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